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Byoul Lee

As seen in: Frontiers
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Articles

Adrenal androgen mediates the association between obesity and accelerated skeletal maturation in children and adolescents

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By Yonsei College, Hye Sun, Byoul Lee
| Frontiers
Abstract Background: Childhood obesity is associated with advanced bone age (BA), but the underlying endocrine mechanisms remain unclear. We investigated the mediating role of dehydroepiandrosterone sulfate (DHEA-S) in the relationship between adiposity and skeletal maturation. Methods: This retrospective study included 1,252 children aged 4–12 years from a single center. Skeletal maturation was assessed using the BA-to-chronological age (CA) ratio.
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