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Byron DeLaBarre on Muck Rack

Byron DeLaBarre

As seen in: BioRxiv
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Articles

Discovery and characterization of FX-909, a covalent inverse agonist of PPARG rationally designed to impose a powerful repressive bias in PPARG for the treatment of PPARG/RXRA-activated muscle-invasive urothelial cancers

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By Byron DeLaBarre, Jacob Stuckey, Jonathan Wilson, Jennifer A Mertz
| BioRxiv
Abstract We report our mechanistic investigation into the conformationally-driven activation bias of PPARG in muscle-invasive urothelial cancer (MIUC) and our efforts to pharmacologically reverse this activation bias through covalent PPARG inverse agonism.
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CCG user group meeting 2016

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By Byron DeLaBarre
| storify.com
Are you sure you want to delete your account? You'll lose everything, forever! Of course not!
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