Multicomponent reactions (MCRs) typically involve the simultaneous combination of three or more reactants in a single vessel, resulting in products that incorporate components from all the reactants in a single step [1]. In comparison to traditional two-component linear synthetic methods, well-designed MCRs offer a more streamlined and efficient approach to accessing complex compounds, utilizing fewer reagents, purification steps, and time [[2], [3], [4], [5], [6]].
