As the sixth most common human disease, periodontitis affects 45 %–50 % of the population worldwide, causing the destruction of periodontal supportive tissues and eventually edentulism [1]. Periodontitis also has a close biological association with various non‐communicable inflammatory disorders [2]. The clinical need for periodontal inflammation control and periodontal tissue repair arises to improve the long-term prognosis of teeth and control the risks of various systemic disorders.