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Acute Myeloid Leukemia With Concurrent NPM1 and RUNX1 Mutations
NPM1 mutation, as a founding genetic event, cooperates with other gene mutations, such as DNMT3A and FLT3, to promote the development of acute myeloid leukemia. NPM1 mutation, however, has been reported to be mutually exclusive with RUNX1 mutation in acute myeloid leukemia cases. In this study, we analyzed mutation panel testing data from a relatively large cohort of rare AML cases with both NPM1 and RUNX1 mutations.
"TET2 Truncating Mutations Predict a Worse Outcome in Blastic Plasmacyt" by Hannah Beird, C Cameron Yin et al.
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Opinion: Funding to fight hate crime is a start, but actions matter, too
Gov. Gavin Newsom has signed legislation that includes more than $157 million for Asian Pacific Islander equity in the 2021-22 California budget. This is a historic three-year investment for California’s growing Asian Pacific Islander community. Nearly $10 million will go toward better data collection. With this critical funding as a first step, we look forward to action by the Legislature.
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