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Keywords kynurenine kynurenine pathway UPLC-MS/MS tryptophan serotonin 1. Introduction Tryptophan (TRP) is an essential amino acid exclusively obtained alimentary in humans and thus plays an important limiting role in protein biosynthesis. TRP is converted into serotonin, tryptamine or metabolized via the kynurenine pathway (KP) and hence a precursor for a variety of bioactive compounds affecting neurotransmission and immune response [1].
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