Cadson College

Table 1 Reagents and tools table Animal experiments and ethics statement All animal experiments in this study were approved by the Animal Care and Use Committee of the Guangzhou Institutes of Biomedicine and Health (GIBH), Chinese Academy of Sciences (CAS), under license number 2016012. The wild-type mice C57BL/6 (stock no. 493) and ICR (stock no. 2021-210) were purchased from Charles River Laboratory.

1 Introduction A profound biological response of specific chemical entities in natural extracts opens new horizons to novel medicines. Natural medicines are derivatives of plants, animals, microbes, marine, and other natural sources that play an important role in the modern healthcare system (Sidra et al., 2014). Some biological molecules exhibit important antioxidant functions, adding to the immune power of plants and animals.