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Caitlin Ann Taylor

As seen in: BioRxiv
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Articles

CRMP/UNC-33 maintains neuronal microtubule arrays by promoting individual microtubule rescue

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By Xing Liang, Kelsie Eichel, Caitlin Ann Taylor, Regina Agulto
| BioRxiv
Abstract Microtubules (MTs) are intrinsically dynamic polymers. In neurons, staggered individual microtubules form stable, polarized acentrosomal MT arrays spanning the axon and dendrite to support long-distance intracellular transport. How the stability and polarity of these arrays are maintained when individual MTs remain highly dynamic is still an open question. Here we visualize MT arrays in vivo in C. elegans neurons with single microtubule resolution.
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Stochastic growth and selective stabilization generate stereotyped dendritic arbors

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By Rebecca Shi, Xue Yan Ho, Li Tao, Caitlin Ann Taylor
| BioRxiv
Abstract Stereotyped dendritic arbors are shaped by dynamic and stochastic growth during neuronal development. It remains unclear how guidance receptors and ligands coordinate branch dynamic growth, retraction, and stabilization to specify dendritic arbors. We previously showed that extracellular ligand SAX-7/LICAM dictates the shape of the PVD sensory neuron via binding to the dendritic guidance receptor DMA-1, a single transmembrane adhesion molecule.
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