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Caitlynn M.L Barrows on Muck Rack

Caitlynn M.L Barrows

As seen in: BioRxiv, Texas Medical Center
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Articles

Human Salivary Gland Stem/Progenitor Cells for Tissue Engineering, SARS-CoV-2 Susceptibility, and Neurointegration

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By Caitlynn M.L Barrows
| Texas Medical Center
Abstract Salivary glands and the saliva they secrete are important for digestion, chewing, and maintaining oral health. Reduced saliva production leads to a decreased quality of life for patients experiencing hyposalivation as a result of disease or injury, thus a large effort has been dedicated to developing materials and medium to recapitulate the structure of the gland for regenerative medicine. In doing so, we have come closer to developing a more complex model to study disease.
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Exploring Spike-Dependent and ACE2-Independent Viral Entry into Salivary Epithelial Cells in the Absence of ACE2

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By Mary C Farach-Carson, Caitlynn M.L Barrows
| BioRxiv
Abstract Abstract: Salivary gland infection by SARS-CoV-2 requires viral entry via routes and mechanisms that remain unresolved. This study examined the expression of the angiotensin-converting enzyme 2 (ACE2) receptor in salivary tissues and basal cell-derived human salivary progenitor cells (hS/PCs), an unstudied potential entry point for SARS-CoV-2.
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