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Callum Parkin

As seen in: Nature, BioRxiv
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Articles

The BRCT domain enhances DNA binding and catalytic efficiency of fungal PARPs

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By Adam Bainbridge, Rohanah Hussain, Callum Parkin, Adam D. Longhurst, Nicolas Helmstetter, Rhys A. Farrer, Sandra Catania, Giuliano Siligardi, Tiberiu-Marius Gianga
| Nature Verified
Abstract Aspergillus fumigatus infections are a major yet often neglected global health challenge magnified by a growing at-risk population, limited treatment options, and the emergence of drug-resistant strains. Regulation of the DNA damage response (DDR) by ADP-ribosylation signalling has recently emerged as an important feature of fungal pathogenesis, but the underlying mechanisms remain largely elusive.
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Dynamic calcium-mediated stress response and recovery signatures in the fungal pathogen, Candida albicans

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By Mariana Almeida, Mark D. Fricker, Claudiu V. Giuraniuc, Callum Parkin
| BioRxiv
Thank you for your interest in spreading the word about bioRxiv. NOTE: Your email address is requested solely to identify you as the sender of this article. Your Email * Your Name * Send To * Enter multiple addresses on separate lines or separate them with commas. Message Subject (Your Name) has forwarded a page to you from bioRxiv Message Body (Your Name) thought you would like to see this page from the bioRxiv website.
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