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Articles by Cameron DA
Analysis of factors influencing the pathological complete remission (ipCR) in patients with internal mammary lymph node metastasis after neoadjuvant chemotherapy
Lymphatic drainage in the breast mainly occurs through the axillary and internal mammary lymph nodes. The ipsilateral ALN drains 75% of the lymph of the breast, while the remaining 25% of the lymph is drained from the IMLNs. Although the IMLNs are defined as regional nodes similar to the ALNs, previous studies have shown that BC cases with IMLN metastasis have a worse prognosis compared to cases involving metastasis to the ALNs (Madsen et al., 2015). Noguchi et al.
Thromboxane biosynthesis in cancer patients and its inhibition by aspirin: a sub-study of the Add-Aspirin trial
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Breast-Conserving Surgery with or without Irradiation in Early Breast Cancer
N Engl J Med. Display options Format doi: 10.1056/NEJMoa2207586. Affiliation 1 From the University of Edinburgh (I.H.K., L.J.W., D.A.C., J.M.D.) and Western General Hospital (W.J.L.J.) - both in Edinburgh.
Phase I open-label study of afatinib plus vinorelbine in patients with solid tumours overexpressing EGFR and/or HER2
This phase Ib study evaluated afatinib plus vinorelbine in patients with advanced solid tumours overexpressing epidermal growth factor receptor (EGFR) and/or human EGFR 2 (HER2). Maximum tolerated doses (MTDs) were determined for afatinib (20, 40 or 50?mg, once daily) combined with standard intravenous vinorelbine (part A; 25?mg?m?2 per week) or oral vinorelbine (part B; 60?mg?m?2 per week, increased to 80?mg?m?2 per week at week 3).
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