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Can Lin

As seen in: Nature, MDPI, Science Magazine, PeerJ, Journal of Risk Model Validation, Physician's Weekly
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Articles by Can Lin

Development and multicenter validation of an AI-driven detection system for DLBCL cells in bone marrow smears

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By Longrong Ran, Yu Hsuan Peng, Xuelian Wu, Zheng Li, Shuyue Chen, Wei Zhang, Xiaojun Xia, Yakun Zhang, Mingyu Zhao, Shuang Chen, Can Lin, Lian Li, Liangmei Li, Jun Li, Xing Wu, Zailin Yang, Yao Liu, Yuanyou Yao
| Nature Verified
Abstract The presence of diffuse large B-cell lymphoma (DLBCL) cells in bone marrow (BM) smears is recognised as a key morphological basis for diagnosing BM involvement by DLBCL. BM involvement directly affects disease staging, treatment strategies, and prognosis assessment. Nevertheless, traditional manual identification of DLBCL cells in BM smears under a microscope is time-consuming, subject to observer variability, and lacks standardization between hospitals.
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Computer Science > Computer Vision and Pattern Recognition

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By Can Lin, Hangjie Yuan
| arXiv
arXivLabs is a framework that allows collaborators to develop and share new arXiv features directly on our website. Both individuals and organizations that work with arXivLabs have embraced and accepted our values of openness, community, excellence, and user data privacy. arXiv is committed to these values and only works with partners that adhere to them. Have an idea for a project that will add value for arXiv's community? Learn more about arXivLabs.
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SRSF3 determines T reg cell fate in antitumor immunity and autoimmunity

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By Xiao Yu, Fan Xia, Bolan Gan, Rong Liang Jia, Jihua Guo, Linyan Yan, Can Lin, Jun Jia, Jun Shao, Dunfang Zhang, Na Liu, Wanjun Chen
| Science Magazine Verified
Abstract INTRODUCTION RESULTS DISCUSSION MATERIALS AND METHODS Acknowledgments Supplementary Materials REFERENCES Information & Authors Metrics & Citations View Options References Figures Tables Media Share Abstract Human FOXP3 shows two isoforms due to exon 2 skipping, and the exon 2 is critical for FOXP3 function in Treg cells. However, the factor(s) regulating its splicing remain unknown.
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MDDeep-Ace: species-specific acetylation site prediction based on multi-domain adaptation

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By Yu Liu, Can Lin, Chaofan Ye, Kangkang Mao
| PeerJ
School of Integrated Circuits, Anhui University, Hefei City, Anhui, China DOI 10.7717/peerj.19649 Academic Editor Liang Wang Subject Areas Biochemistry, Bioengineering, Bioinformatics Keywords Acetylation, Species-specific, Deep learning, Multi-domain adaptation Copyright © Licence This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, reproduction and adaptation in any medium and for any purpose...
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How Does African Swine Fever Virus Evade the cGAS-STING Pathway?

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By Can Lin, Chenyang Zhang, Nanhua Chen, François Meurens
| MDPI
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
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Online attention and directors’ and officers’ liability insurance: evidence from Chinese listed firms

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By Can Lin, Huobao Xie
| Journal of Risk Model Validation Verified
Tweet Facebook LinkedIn Save this article Send to Print this page Our theoretical analysis and empirical tests show that online attention increases purchases of insurance. The analysis and tests of the mediating mechanisms show that online attention increases purchases of D&O insurance by improving investor protection and exacerbating managerial career concerns.
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Cryotherapy Attenuates Inflammation via the lncRNA SNHG1/miR-9-5p/NFKB1 Regulatory Axis in Periodontal Ligament Cells

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By Can Lin, Miaomiao Liu, Jihua Guo, Rong Liang Jia
| MDPI
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MIF promotes Th17 cell differentiation in Hashimoto’s thyroiditis by binding HVEM and activating NF-κB signaling pathway.

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By Zijian Liu, Zhihao Li, Can Lin, Guozhi Yan
| Physician's Weekly
Hashimoto’s thyroiditis is a typical thyroid autoimmune disease and Th17 cells are crucial in its development. In recent years, MIF (Macrophage Migration Inhibitory Factor) has been found to promote the secretion of IL-17A and the production and differentiation of Th17 cells. However, the specific mechanism of it remains unclear. Here, we found that the expression of MIF, IL-17A and HVEM (Herpes Virus Entry Mediator) were up-regulated in HT patients.
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SRSF3-Mediated Ki67 Exon 7-Inclusion Promotes Head and Neck Squamous Cell Carcinoma Progression via Repressing AKR1C2

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By Miaomiao Liu, Can Lin, Qiwei Huang, Jun Jia
| MDPI
Open AccessArticle by Miaomiao Liu 1, Can Lin 1, Qiwei Huang 2,3, Jun Jia 1,4,*, Jihua Guo 1,5 and Rong Jia 1,2,* 1 The State Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei-MOST) & Key Laboratory of Oral Biomedicine Ministry of Education, School & Hospital of Stomatology, Wuhan University, Wuhan 430079, China 2 RNA Institute, Wuhan University, Wuhan 430072, China 3 State Key Laboratory of Virology and Hubei Key Laboratory of Cell Homeostasis, College of Life Science,...
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Construction of iron and oxygen co-doped nickel phosphide based on MOF derivatives for highly efficient and long-enduring water splitting

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By Can Lin, Huihui Jin, Pengyan Wang, Dingqian Wang
| Royal Society of Chemistry Verified
Construction of iron and oxygen co-doped nickel phosphide based on MOF derivatives for highly efficient and long-enduring water splitting The exploitation of high catalytic activity electrocatalysts with abundant earth reserves is the prerequisite for extensive hydrogen production from electrolyzed water.
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Iron-doped Cobalt Phosphide Nano-Electrocatalyst Derived from Metal-Organic Framework for Efficient Water Splitting

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By Pengyan Wang, Huihui Jin, Jiahuan Zhao, Can Lin
| Royal Society of Chemistry Verified
Iron-doped Cobalt Phosphide Nano-Electrocatalyst Derived from Metal-Organic Framework for Efficient Water Splitting The development of hydrogen energy relies to a large extent on electrocatalysts that are highly-efficient and widely-sourced.
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