Cankut Cubuk on Muck Rack

Cankut Cubuk

As seen in: Nature, MDPI, Arthritis Research & Therapy
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Articles

Deep molecular profiling of synovial biopsies in the STRAP trial identifies signatures predictive of treatment response to biologic therapies in rheumatoid arthritis | Nature Communications

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By Myles J. Lewis, Cankut Cubuk, Elisabetta Sciacca, Rachel Lau Verified, Liliane Fossati-Jimack, Alessandra Nerviani, Felice Rivellese, Costantino Pitzalis
| Nature Verified
Abstract Approximately 40% of patients with rheumatoid arthritis do not respond to individual biologic therapies, while biomarkers predictive of treatment response are lacking.
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Analgesic targets identified in mouse sensory neuron somata and terminal pain translatomes

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By Ali Khan Bangash, Cankut Cubuk, Federico Iseppon, Rayan Haroun
| biorxiv.org
Abstract The relationship between transcription and protein expression is complex. We identified polysome-associated RNA transcripts in the somata and central terminals of mouse sensory neurons in control, painful (+ Nerve Growth Factor (NGF)) and pain-free conditions (Nav1.7 null mice). The majority (98%) of translated transcripts are shared between male and female mice in both the somata and terminals. Some transcripts are highly enriched in the somata or terminals.
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Crosstalk between Metabolite Production and Signaling Activity in Breast Cancer

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By Cankut Cubuk, Carlos Loucera, María Peña-Chilet, Joaquín Dopazo
| MDPI
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