Cardiometabolic Disorders

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Widefield 60× images of tissues stained for DAPI and Na/K-ATPase were analyzed for cell area and cell circularity through custom ImageJ scripts implementing the MorphoLibJ plugin,50 which segments an image based on pre-defined markers [supplementary material, Fig. 3(a)]. Markers for each cell were identified by using the find maxima function on the DAPI stain. Then, the Na/K-ATPase stain was segmented using MorphoLibJ marker-controlled segmentation.

To view the full text, please login as a subscribed user or purchase a subscription. Click here to view the full text on ScienceDirect. Fig. 1 Illustration of possible DPP10-induced effects on the human ventricular (top) and atrial (bottom) action potential based on mathematical modeling (see text). In each Panel the DPP10-induced change is shown as broken red lines.