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Caretha L. Creasy on Muck Rack

Caretha L. Creasy

As seen in: Nature
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Articles

Targeting epigenetic modifications in cancer therapy: erasing the roadmap to cancer

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By Helai P. Mohammad, Olena Barbash, Caretha L. Creasy
| Nature Verified
Abstract Epigenetic dysregulation is a common feature of most cancers, often occurring directly through alteration of epigenetic machinery. Over the last several years, a new generation of drugs directed at epigenetic modulators have entered clinical development, and results from these trials are now being disclosed. Unlike first-generation epigenetic therapies, these new agents are selective, and many are targeted to proteins which are mutated or translocated in cancer.
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