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Carlotta Barelli

As seen in: BioRxiv
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Articles

Glioblastoma stem cell morphotypes convey distinct cell states and clinically relevant functions

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By Carlotta Barelli, Matteo Bonfanti, Filippo Mirabella, Dario Ricca
| BioRxiv
Abstract Glioblastoma (GBM) is an aggressive brain tumor with a poor prognosis, driven by therapy resistance and invasion into healthy tissue. GBM stem cells (GSCs) play a central role in tumor progression, yet their biology remains poorly understood. Leveraging the similarities between GSCs and embryonic neural progenitor cells, we explore the relationship between GSC morphology and functional states.
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Morphoregulatory ADD3 underlies glioblastoma growth and formation of tumor-tumor connections

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By Carlotta Barelli, Flaminia Kaluthantrige Don, Raffaele Iannuzzi, Ilaria Bertani
| BioRxiv
Abstract Glioblastoma is a major unmet clinical need characterized by striking inter- and intra-tumoral heterogeneity and a population of glioblastoma stem cells (GSCs), conferring aggressiveness and therapy resistance. GSCs communicate through a network of tumor-tumor connections (TTCs), including nanotubes and microtubes, promoting tumor progression. However, very little is known about the mechanisms underlying TTC formation and overall GSC morphology.
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Haemorrhage of human foetal cortex associated with SARS-CoV-2 infection

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By Catalina Moreno, Marco Massimo, Carlotta Barelli
| ncbi.nlm.nih.gov
Skip to main content Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation Journal List Brain PMC9976976 As a library, NLM provides access to scientific literature. Inclusion in an NLM database does not imply endorsement of, or agreement with, the contents by NLM or the National Institutes of Health. Learn more about our disclaimer.
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