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Carlotta Barison

As seen in: Cell Reports Medicine
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Opantimirs: A class of antagonizing microRNAs that upregulate Opa1 and improve mitochondrial and disuse myopathies

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By Andre Djalalvandi, Keisuke Takeda, Francesca Grespi, Hualin Fan, Tiago Fonseca, Leonardo Nogara, Saman Sharifi, Carlotta Barison, Martina Semenzato, Akiko Omori, Raffaele Cerutti, Davide Steffan, Lorenza Tsansizi, Valeria Balmaceda, Lukas Alan, Camilla Bean, Bert Blaauw, Carlo Viscomi, Luca Scorrano
| Cell Reports Medicine Verified
Keywords OPA1 microRNAs antimiRs mitochondrial ultrastructure cristae remodeling mitochondrial myopathies disuse myopathies miR-148/152-3p family miR-128-3p Introduction Mitochondrial diseases are a group of clinically heterogeneous conditions that arise from oxidative phosphorylation (OXPHOS) malfunction due to defects in respiratory chain complexes.1 These disorders affect one in every 2,000 individuals, can manifest in infancy or adulthood, and are caused by pathogenic mutations in either...
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