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Keywords senescence ferroptosis PUFA DGLA aging senolytic metabolism lipid peroxidation obesity desaturation Introduction Throughout their lifespans, cells are subject to various stressors, including macromolecular damage, epigenetic disruption, metabolic shifts, and mitochondrial dysfunction.1,2 If unresolved, accumulation of these insults over time can result in degenerative conditions and cancer, necessitating activation of protective cellular responses.
Introduction Click to copy section linkSection link copied! Mycobacterium abscessus (M.ab) is a member of the nontuberculous mycobacteria (NTM), which includes a diverse set of environmental bacteria typically found in soil, dust, water, and other natural sources.
Introduction Click to copy section linkSection link copied! Nontuberculous mycobacteria (NTM) are a group of environmental bacteria and are generally nonpathogenic. However, they can cause severe lung infections in immunocompromised individuals or those with pre-existing lung conditions such as cystic fibrosis (CF) and chronic obstructive pulmonary disease (COPD). (1−3) Mycobacterium abscessus (M. ab) is one of the most common NTM species identified in CF patients with lung diseases. M.
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