Carmelo J. Mastrandrea on Muck Rack

Carmelo J. Mastrandrea

As seen in: Wiley Online Library, Canadian Journal of Cardiology
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Effects of 14 days of head-down bed rest with or without exercise, and subsequent recovery on bone turnover, density and structure in older adults

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By Guy Hajj-Boutros, Andréa Faust, Carmelo J. Mastrandrea
| Wiley Online Library Verified
1 INTRODUCTION Extended periods of physical inactivity, such as those experienced during bed rest, lead to rapid and pronounced declines in physiological function (Sibonga et al., 2007). Head-down tilt bed rest (HDBR) at 6° is an established terrestrial model that simulates the unloading effects of microgravity, enabling controlled investigation of musculoskeletal adaptations and evaluation of potential countermeasures (Hargens & Vico, 2016).
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