Carola Staedele

Abstract While temperature fluctuations pose significant challenges to the nervous system, many vital neuronal systems in poikilothermic animals function over a broad temperature range. Using the gastric mill pattern generator in the Jonah crab, we previously demonstrated that temperature-induced increases in leak conductance disrupt neuronal function and that neuropeptide modulation provides thermal protection.

Abstract Temperature fluctuations pose significant challenges to the nervous system, in particular in poikilothermic animals that lack active temperature regulation. Nevertheless, many vital neuronal systems in these animals function over a broad temperature range, making them ideal to study the mechanisms of temperature robustness.