Carolina Lin Windham on Muck Rack

Carolina Lin Windham

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Articles

NSD2 inhibitors rewire chromatin to treat lung and pancreatic cancers - Nature

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By Jinho Jeong, Simone Hausmann, Andy Gonzalez, Xiaoyin Lu, Joanna K. Lempiäinen, Eric Bareke, Rui Zhi Dong, Reinnier Padilla, Dylan Husmann, Gerry Shipman, Emily Zahn, Laiba Khan, Liz Marie Albertorio-Sáez, Iwona Czaban, Michael-Christopher Keogh, Benjamin Garcia, Jacek Majewski, Pawel K. Mazur, Tourkian Chasan, Eva Brill, Danielle N. Maryanski, Carolina Lin Windham
| Nature Verified
Abstract NSD2 catalyses the epigenetic modification H3K36me2 (refs. 1,2) and is a candidate convergent downstream effector of oncogenic signalling in diverse malignancies3,4,5. However, it remains unclear whether the enzymatic activity of NSD2 is therapeutically targetable.
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