Is this you? As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.
Claim your profile
Introduction Hypothalamic pro-opiomelanocortin (POMC)-expressing neurons in the arcuate nucleus (ARC) play key roles in regulating metabolism and body weight. POMC neurons respond to adipose-derived leptin by signalling to “satiety neurons” expressing the melanocortin receptor, ultimately inhibiting food intake and promoting energy expenditure (Lee and Blackshaw, 2014; Anderson et al., 2016; Quarta et al., 2020).
Highlights • Foxp1 is transiently expressed by apical radial glia (aRG) during early corticogenesis • Foxp1 promotes self-renewing vertical cell divisions and aRG maintenance • Foxp1 gates the time window of deep-layer neurogenesis • FOXP1 is prominently associated with aRG and basal RG expansion in human neocortex Summary The laminar architecture of the mammalian neocortex depends on the orderly generation of distinct neuronal subtypes by apical radial glia (aRG) during embryogenesis.
As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.
