Caroline Beck Adiels

An in vivo mimetic Liver-Lobule-Chip (LLoC) for stem cell maturation and zonation of hepatocyte-like cells on chip. In vitro cell culture models play a crucial role in preclinical drug discovery. To achieve optimal culturing environments and establish physiologically relevant organ-specific conditions, it is imperative to replicate in vivo scenarios when working with primary or induced pluripotent cell types.