By Cassie Homer, Senior Managing Editor Save to PDF April 12, 2022 By <em>By Cassie Homer, Senior Managing Editor</em> The FDA granted HPN328, a delta like ligand 3 (DLL3) targeting therapy, orphan drug designation for the treatment of patients with small cell lung cancer, according to a press release from the manufacturer. The manufacturer used its Tri-specific T cell Activating Construct (TriTAC) platform to develop the drug.