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Impact of treatment duration on the effectiveness of opioid analgesia: a systematic review and meta-analysis
Abstract Background Opioid use can heighten pain perception over time. Aim To determine whether the effectiveness of opioid analgesia diminishes with treatment duration in those with chronic low back pain or osteoarthritis. Design and setting Systematic review of randomised trials comparing opioids with placebo/opioid-minimised pain management strategies in those with chronic low back pain or osteoarthritis.
Impact of Treatment Duration on the Effectiveness of Opioid Analgesia: A Systematic Review and Meta-Analysis
Abstract Background Opioid use can heighten pain perception over time. Aim To determine whether the effectiveness of opioid analgesia diminishes with treatment duration in those with chronic low back pain or osteoarthritis. Design and setting Systematic review (January 22, 2025) of randomized trials comparing opioids to placebo/opioid-minimized pain management strategies in those with chronic low back pain or osteoarthritis.
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