Catherine Leroy

A new law dated 14 July 2023 establishing a national screening mechanism for foreign direct investments that may undermine security or public order for the purpose of implementing Regulation (EU) 2019/452 of the European Parliament and of the Council of 19 March 2019 establishing a framework for screening foreign direct investments in the Union, as amended, has been published in Memorial A411 on 18 July 2023. Its entry into force is scheduled for 1 September 2023.

1. Introduction Nonsense mutations affect about 10% of patients with genetic diseases [1]. They are among the most impactful, because they very often lead to the absence of expression of the mutated gene; a quality control mechanism called nonsense-mediated mRNA decay (NMD) recognizes and rapidly degrades mRNAs carrying a premature termination codon [2,3,4,5]. This mRNA surveillance mechanism is highly regulated [6] and entwined in interactions with various metabolic pathways [7].

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