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Catherine Robbe Masselot on Muck Rack

Catherine Robbe Masselot

As seen in: Nature
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Transcriptome, glycome, and mucinome analysis reveal zinc is essential for the composition of mucus in the human goblet cell model HT-29-MTX

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By Renaud LEONARD, Heike Sprenger, Keira E. Mahoney, Claudia Matthaeus, Franziska Ebert, Marvin Wolf, François Foulquier, Albert Braeuning, Stacy A. Malaker, Maria Maares, Christoph Schüßler, Nara Chung, Tari Rödel, Susanne Thomsen, Esther Ocket, Jordan Denis, Willy Morelle, Catherine Robbe Masselot
| Nature Verified
Abstract Zinc (Zn) deficiency affects approximately 1 billion people worldwide with severe consequences for their health, including increased intestinal infections, inflammation, and diarrhea. Accordingly, the intestinal defense barrier is compromised, leading to epithelial destruction and alteration of mucus. However, the processes and the extent to which Zn deficiency affects mucin synthesis in intestinal goblet cells (GCs) remain poorly understood.
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