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Catriona Patterson

As seen in: Nature, MDPI, Scotland on Sunday

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Articles

The transmission-blocking dynamics of Plasmodium falciparum sexual-stage antibody responses in a six-year cohort of Ugandan children and adults

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By Sara Blanken, Patience Nayebare, Gerine Nijman, Karina Teelen, Rianne Stoter, Geert-Jan van Gemert, Wouter Graumans, Tate Oulton, Catriona Patterson, Abdoulie Drammeh, Judith M. Bolscher, Lauren Cohee, Sanjai Kumar, Noah Sather, Alvaro Molina-Cruz, Emmanuel Arinaitwe, Moses Kamya, Koen J. Dechering, Grant Dorsey, Chris Drakeley, Matthijs M. Jore, Teun Bousema, William Stone, Jonathan Briese, Marloes de Bruijni
| Nature Verified
Abstract Individuals naturally infected with Plasmodium can develop antibodies against the parasite’s sexual stages that may inhibit onward transmission when ingested they are during a mosquito vector’s blood meal. Our study reports immune signatures and longitudinal dynamics of naturally occurring transmission-reducing activity (TRA) in a Ugandan cohort.
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Author Correction: Multiplex bead assays enable integrated serological surveillance and reveal cross-pathogen vulnerabilities in Zambezia Province, Mozambique | Nature Communications

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By Andrea C. Carcelen, Saki Takahashi, Catriona Patterson, Melissa M Higdon, Christopher Drakeley
| Nature Verified
Correction to: Nature Communications https://doi.org/10.1038/s41467-025-62305-9, published online 26 August 2025 In the version of the article initially published, in the Fig. 4 colour bar header and in the first sentence of the caption, the word “log” was missing from the text now reading “Adjusted log OR” and “Adjusted log odds ratios,” respectively. The figure and caption are updated in the HTML and PDF versions of the article.
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Multiplex bead assays enable integrated serological surveillance and reveal cross-pathogen vulnerabilities in Zambezia Province, Mozambique - Nature Communications

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By Andrea C. Carcelen, Saki Takahashi, Catriona Patterson, Melissa M Higdon, Christopher Drakeley
| Nature Verified
Abstract Multiplex serological assays simultaneously measure antibodies to multiple antigens, furnishing insights into exposure and susceptibility to several pathogens and cross-pathogen vulnerabilities. Our serosurvey tests dried blood spots from 1292 individuals for IgG antibodies to 35 antigens from 18 pathogens using a multiplex bead assay for vaccine preventable diseases, malaria, SARS-CoV-2, neglected tropical diseases, and enteric pathogens in Mozambique.
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