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Cécile Guillon

As seen in: Nature, BMJ Open Diabetes Research & Care
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Articles by Cécile Guillon

Inhibition of endogenous TGF-β normalizes extracellular matrix deposition in hiPSC-derived fibroblasts

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By Lucile Guillot, Lara Jobeili, Cécile Guillon, Sophie Clement, Sophie Clément Verified, Christelle Bonod, Dominique Sigaudo-Roussel, Nicolas Picard, Léa Cassulino, Luciano Figueiredo Borges, Chalot Marion, Julien Coutier, Ulrich Valcourt, Catherine Moali
| Nature Verified
Abstract Fibroblasts are mesenchymal cells with essential functions for connective tissue homeostasis and repair through the production and organization of the extracellular matrix (ECM). Most reconstructed skin models used in research and skin-related applications rely on fibroblasts to produce ECM. Despite their shared functions, human fibroblasts from different origins exhibit heterogeneity in age, morphotype, and localization.
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Glycation by glyoxal leads to profound changes in the behavior of dermal fibroblasts

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By Cécile Guillon, Sandra Ferraro, Sophie Clement, Sophie Clément Verified, Marielle Bouschbacher
| BMJ Open Diabetes Research & Care Verified
Pathophysiology/complications Glycation by glyoxal leads to profound changes in the behavior of dermal fibroblasts Cécile Guillon1,2, Sandra Ferraro2, Sophie Clément1, Marielle Bouschbacher1, Dominique Sigaudo-Roussel2, http://orcid.org/0000-0002-7180-2727Christelle Bonod2 1Urgo Research Innovation and Development, Chenôve, France 2Université de Lyon, Université Claude Bernard Lyon 1, CNRS, LBTI UMR 5305, Lyon, France Correspondence to Dr Christelle Bonod; christelle.bonod{at}ibcp.fr Abstract...
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