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Celia Burgos Sequeros

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Articles

Central role of glycosylation processes in human genetic susceptibility to SARS-CoV-2 infections with Omicron variants - Nature Genetics

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By Frank Geller, Xiaoping Wu, Vilma Lammi, Erik Abner, Angus Burns, Niklas Andersson, Bitten Aagaard, Sofie Bliddal, Søren Brunak, Jonas Bybjerg-Grauholm, Maria Didriksen, Khoa Manh Dinh, Christian Erikstrup, Kirsten Grønbæk, Kathrine Agergård Kaspersen, Christina Mikkelsen, Henriette Svarre Nielsen, Janna Nissen, Niels Tommerup, Anders Hviid, Erik S. Sørensen, Ole Birger Pedersen, Hanna M. Ollila, Celia Burgos Sequeros
| Nature Verified
Abstract The host genetics of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have previously been studied based on cases from the earlier waves of the pandemic in 2020 and 2021, identifying 51 genomic loci associated with infection and/or severity. SARS-CoV-2 has shown rapid sequence evolution, increasing transmissibility, particularly for Omicron variants, which raises the question of whether this affected the host genetic factors.
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