Centro Regionale Antidoping

A new class of synthetic cannabinoids called OXIZIDs has emerged in recent years. This class consists of compounds with oxindole cores and hydrazide/hydrazone linker moieties and has often been described as being designed to circumvent a Chinese class-wide ban that was effective as of July 1, 2021.

Sample collection and preparation In this study, we focus on two purposive samples of adults—from the US and from Italy. Hair samples were collected in 2022 in the US (60 samples, from an ongoing rapid street reporting surveillance study being conducted throughout various US cities by the National Drug Early Warning System) [28] and in Italy (60 samples, from harm reduction services in Northern Italy), according to international guidelines [29].