Chandana B. Herath

#Correspondence to: Dr. Eric Lazartigues, PhD; Louisiana State University Health, School of Medicine, Cardiovascular Center of Excellence, 533 Bolivar Street, New Orleans, LA 70112.

1 Introduction Hepatic fibrosis, marked by the excessive buildup of extracellular matrix proteins, signifies a progressive liver ailment capable of culminating in cirrhosis and liver failure (Gines et al., 2021). Hence, prioritizing the treatment of hepatic fibrosis before its progression to cirrhosis or liver failure becomes critical. The liver is an important energy metabolism organ that participates in processes such as glucose metabolism and lipid metabolism (Rui, 2014).

Introduction Liver diseases are responsible for almost two million deaths per year globally (Asrani et al., 2019). At present, liver disorders are considered as the 11th cause of mortality and at an accelerating pace for incidence (Griffin et al., 2023).