Chang Liu on Muck Rack

Chang Liu

China
As seen in: Arthritis & Rheumatology, Color Research & Application, Wiley, Wiley Online Library, British Pharmacological Society, New Phytologist, Journal of Accounting and Public Policy, MDPI, ACS Publications, American Chemical Society and
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Articles

Sodium Butyrate Attenuates Sevoflurane-Induced Impaired Myelination and Neurobehavioral Deficits in Neonatal Mice via the H3K9ac/BDNF/TrkB Pathway

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By Chang Liu, Xinyao Bai, Xinyue Liu
| Wiley Online Library Verified
1 Introduction General anesthesia (GA) is an indispensable life-support modality in modern surgery, and millions of infants and young children worldwide receive GA each year for diagnostic and therapeutic purposes [1]. Sevoflurane, owing to its favorable safety profile, rapid onset, and good tolerability, has become a widely used inhalational general anesthetic in clinical practice [2]. Notably, accumulating evidence has indicated that sevoflurane has potential neurotoxicity.
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Fangchinoline alleviates hypertensive heart failure via PGC-1α/STAT6/PPARγ activation of mitophagy against ferroptosis

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By Chang Liu, Zhuoqun Wang, Linxin Zhang
| British Pharmacological Society
CONFLICT OF INTEREST STATEMENT The authors declare that they have no conflict of interest. DATA AVAILABILITY STATEMENT The data that support the findings of this study are available from the corresponding author upon reasonable request. Some data may not be made available because of privacy or ethical restrictions. Supporting Information Filename Description bph70552-sup-0001-supporting_informaiton.docxWord 2007 document , 272 KB Table S1: Primer sequences for qPCR assay.
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An emergent disease-associated motor neuron state precedes cell death in ALS

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By Olivia Gautier, Jacob Blum, Thao Nguyen Verified, Thảo Nguyen, Shaolong Cao, Sandy Klemm, Mai Yamakawa, Dann Huh, Jessica Hurt, Nasa Sinnott-Armstrong, Yi Zeng, Juliane Bombosch, Chang Liu, Lisa Encarnacion, Kevin A. Guttenplan, Derek Chen, Arwa Kathiria, Luke Zhao, Stephen Moore, Don W. Cleveland, John Ravits, Jessica Rexach, William J. Greenleaf, Aaron D. Gitler, Alex Meng, Kailee Ong
| Cell Press Verified
Keywords ALS neurodegeneration spinal cord motor neuron selective vulnerability snRNA-seq snATAC-seq spatial transcriptomics cell states microglial activation Introduction Amyotrophic lateral sclerosis (ALS) is a progressive disorder distinguished by degeneration of motor neurons in the brain and spinal cord. Motor neuron loss impairs mobility, dexterity, speech, and swallowing and ultimately causes fatal paralysis. ALS is a cruelly rapid disease.
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