Channabasappa Shivaprasad

CASE REPORT article Volume 16 - 2025 | https://doi.org/10.3389/fendo.2025.1746210 Introduction Euglycemic ketoacidosis (EKA) is a rare but serious metabolic complication characterized by high anion gap acidosis, ketonemia, and relatively normal blood glucose levels (typically <200 mg/dL) (2–4). Traditionally associated with diabetes mellitus, EKA is now increasingly recognized in SGLT2 inhibitor therapy, even in non-diabetic patients (2, 6).

The differential diagnosis of a girl presenting with primary amenorrhoea includes numerous conditions. Often, patients of 46XY disorder of sex development (DSD) are reared as girl and present with primary amenorrhoea. Their further evaluation to reach the final diagnosis is often a great challenge. In this article, we report a challenging case of 46XY DSD presented with primary amenorrhoea.

Publication HistoryPublished online: March 07, 2018Accepted: March 1, 2018; Received in revised form: January 24, 2018; Received: October 21, 2017;