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Chaokai Ba on Muck Rack

Chaokai Ba

As seen in: Frontiers
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Articles

Metabolic symbiosis and competition: the dual nature of TAM-tumor cell cross-talk in tumor progression

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By Zefan Wang, Huiting Zhu, Shenxian Qian, Chaokai Ba, Shizheng Tong
| Frontiers
Abstract Cancer cells and tumor associated macrophages (TAMs) engage in a sophisticated metabolic symbiosis within the tumor microenvironment (TME), where reciprocal metabolite exchange drives immune evasion and malignant progression. This review posits that TAMs functional plasticity is not merely a consequence but a driver of tumor fitness, governed by extensive metabolic rewiring.
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