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Introduction. Shiga toxin-producing Escherichia coli (STEC) are a group of bacteria that cause severe bloody diarrhoea and haemolytic uraemic syndrome and are associated with neurological complications and potentially life-threatening infections. Children under five and elderly individuals are particularly vulnerable to STEC infections.
Monosaccharide-Based Synthetic TLR4 Agonist Enhances Vaccine Efficacy against Pseudomonas aeruginosa Challenge
Adjuvants play a vital role in vaccine development. They are critical in tailoring subunit vaccine responses by enhancing immune responses and the duration of the response through a variety of mechanisms. Adjuvants stimulate innate immunity by directly interacting with pattern recognition receptors or inducing cellular stress, leading to the release of immunostimulatory and inflammatory signals.
Development of acute Pseudomonas aeruginosa and Acinetobacter baumannii lung mono-challenge models in mice using oropharyngeal aspiration
Article metrics loading... /content/journal/acmi/10.1099/acmi.0.000860.v3 Download as PowerPoint /deliver/fulltext/acmi/6/11/acmi000860.v3.html?itemId=/content/journal/acmi/10.1099/acmi.0.000860.v3&mimeType=html&fmt=ahah References Diggle SP, Whiteley M. Microbe Profile: Pseudomonas aeruginosa: opportunistic pathogen and lab rat. Microbiology 2020; 166:30–33 [View Article] [PubMed] [Google Scholar] Ayoub Moubareck C, Hammoudi Halat D.
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