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Chariya Peeyatu on Muck Rack

Chariya Peeyatu

As seen in: BioRxiv
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Articles

Targeting therapeutic nanoparticles to the glioblastoma resection margin by harnessing post-operative spatiotemporal blood-brain barrier disruption

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By Lorena F Fernandes, Chariya Peeyatu, Ben Dickie, Yu Ho
| BioRxiv
Abstract Resection surgery is the first-line therapy for glioblastoma (GBM) that is performed in >70% of patients, typically within days of suspected diagnosis. Current protocols for follow-on chemoradiotherapy have shown only modest efficacy in eliminating residual disease, leading to inevitable tumour recurrence. There remains a need for new approaches to swiftly and effectively treat post-operative residual disease to prevent the rapid early progression of recurrent GBM.
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