Charlene Lancaster

Scientists often encounter translational barriers when moving drug candidates from the laboratory to the clinic. Written byCharlene Lancaster, PhD Driven by the high failure rates of new drugs, scientists are now exploring why candidates fall short and developing strategies to overcome translational barriers. Image credit:©iStock.com, elenabs Register for free to listen to this article Bringing a new drug to patients requires more than just identifying a promising candidate.

Jim Sun examines how Mycobacterium tuberculosis evades human defenses and forges new ways to control this deadly bacterial pathogen. Written byCharlene Lancaster, PhD For millennia, tuberculosis has persisted as a deadly respiratory disease afflicting humans worldwide. Image credit:©STOCK.ADOBE.COM/ Dr_Microbe Register for free to listen to this article For generations, a devastating lung disease has ravaged communities, killing adults and children alike.

A cutting-edge spatial transcriptomics approach enables researchers to map RNA distribution at subcellular resolution. Written byCharlene Lancaster, PhD By analyzing RNA localization within subcellular compartments, scientists can gain a clearer understanding of how spatial organization influences RNA regulation in health and disease. Image credit:© iStock.com, urfinguss Register for free to listen to this article RNA partitioning is critical for cell fate decisions and overall cellular function.