Is this you? As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.
Claim your profile
Articles by Charlotte Avanzi
Antimicrobial resistance surveillance: a crucial pillar for sustainable leprosy control and chemoprophylaxis
Introduction Leprosy, a neglected tropical disease caused by Mycobacterium leprae, is among the oldest documented infectious diseases, with historical references dating back as far as 2000 BCE.1 Despite substantial advances in prevention, treatment, and control, leprosy remains a public health concern, particularly in low-income and middle-income countries, where poverty-related factors contribute to its ongoing transmission.2 Without early diagnosis and treatment, including prevention and...
Leprosy
Get full text access Log in, subscribe or purchase for full access. References 1. Han, XY ∙ Seo, YH ∙ Sizer, KC ∙ et al. A new Mycobacterium species causing diffuse lepromatous leprosy Am J Clin Pathol. 2008; 130:856-864 2. Hansen, GA On the etiology of leprosy Br Foreign Med Chir Rev. 1875; 55:459-489 3. Collin, SM ∙ Lima, A ∙ Heringer, S ∙ et al. Systematic review of Hansen disease attributed to Mycobacterium lepromatosis Emerg Infect Dis. 2023; 29:1376-1385 4.
Pre-European contact leprosy in the Americas and its current persistence
Article Dans Une Revue Science Année : 2025 Pre-European contact leprosy in the Americas and its current persistence Domaines Origine Fichiers produits par l'(les) auteur(s) pasteur-05106303 , version 1 (11-06-2025) pasteur-05106303 , version 2 (11-06-2025) Maria Lopopolo, Charlotte Avanzi, Sebastian Duchene, Pierre Luisi, Alida de Flamingh, et al.. Pre-European contact leprosy in the Americas and its current persistence. Science, In press, pp.eadu7144. ⟨10.1126/science.adu7144⟩.
Une nouvelle étude montre que la lèpre existait en Amérique bien avant l’arrivée des Européens
[Un article de The Conversation écrit par Nicolas Rascovan - Chercheur à l'Institut Pasteur, Université Paris Cité - Charlotte Avanzi - Assistant Professor, Colorado State University - et Maria Lopopolo - Chercheur à l'Institut Pasteur, Université Paris Cité] La lèpre est une maladie chronique ancienne qui se manifeste par des lésions de la peau, des nerfs périphériques, de la muqueuse des voies respiratoires supérieures ainsi que des yeux.
Pre-European contact leprosy in the Americas and its current persistence
Abstract Leprosy, primarily caused by Mycobacterium leprae, is considered a disease introduced into the Americas during European colonization. However, the recent discovery of a second pathogen causing leprosy, M. lepromatosis, mainly found in the Americas, challenges this view. Here, we show that M. lepromatosis infected humans in the Americas before European contact. By screening 389 ancient and 408 contemporary samples, we have expanded the genetic data available for the species.
Une nouvelle étude montre que la lèpre existait en Amérique bien avant l’arrivée des Européens
Longtemps considérée comme une maladie infectieuse introduite en Amérique par les colonisateurs européens, la lèpre pourrait en fait avoir une histoire bien plus ancienne et plus complexe sur le continent. Une nouvelle étude internationale publiée aujourd’hui dans la revue Science, révèle que Mycobacterium lepromatosis, une bactérie récemment identifiée qui cause la lèpre, infecte les humains en Amérique depuis au moins 1 000 ans, soit plusieurs siècles avant le contact européen.
Mycobacterium leprae in Armadillo Tissues from Museum Collections, United States
Disclaimer: Early release articles are not considered as final versions. Any changes will be reflected in the online version in the month the article is officially released. Mycobacterium leprae in Armadillo Tissues from Museum Collections, United States Daniel Romero-Alvarez , Daniel Garzon-Chavez, Mary Jackson, Charlotte Avanzi, and A. Townsend Peterson Author affiliations: Universidad de las Américas, Quito, Ecuador (D. Romero-Alvarez); University of Kansas, Lawrence, Kansas, USA (D.
Leprosy in wild chimpanzees
Leprosy in wild chimpanzees Kimberley Jane Hockings, Benjamin Mubemba, Charlotte Avanzi, Kamilla Pleh, Ariane Dux, Elena Bersacola, Joana Bessa, Marina Ramon, Sonja Metzger, Livia V Patrono, Jenny E Jaffe, Andrej Benjak, Camille Jane Bonneaud, Philippe Busso, Emmanuel Couacy-Hymann, Moussa Gado, Sebastien Gagneux, Roch C Johnson, Mamoudou Kodio, Joshua G Lynton-Jenkins, Irina Morozova, Kerstin Matz-Rensing, Aissa Regalla, Abilio R Said, Verena J.
Emergence of Mycobacterium leprae Rifampin Resistance Evaluated by Whole-Genome Sequencing after 48 Years of Irregular Treatment
Epidemiology and Surveillance Charlotte Avanzi, Raquel Cristina Maia, Andrej Benjak, José Augusto Nery, Anna Maria Sales, Alice Miranda, Nadia Cristina Duppre, Amanda Nogueira Brum Fontes, Tatiana Pereira da Silva, Roberta Olmo Pinheiro, Fernanda Neves-Manta, Suelen Justo Maria Moreira, Philippe Busso, Euzenir Nunes Sarno, Phillip Noel Suffys, Stewart Thomas Cole, Milton Ozório Moraes DOI: 10.1128/AAC.00330-20 ABSTRACT A case of Mycobacterium leprae rifampin resistance after irregular...
Leprosy in red squirrels in the UK
Leprosy in red squirrels in the UK Anna-Katarina Schilling, Jorge Del-Pozo, Peter W. W. Lurz, Karen Stevenson, Charlotte Avanzi, Craig M. Shuttleworth, Stewart T. Cole and Anna L.
Highly Reduced Genome of the New Species Mycobacterium uberis, the Causative Agent of Nodular Thelitis and Tuberculoid Scrotitis in Livestock and a Close Relative of the Leprosy Bacilli
ABSTRACTNodular thelitis is a chronic enzootic infection affecting dairy cows and goats. The causative agent was recently shown to be related to the leprosy-causing bacilli Mycobacterium leprae and Mycobacterium lepromatosis. In this study, the genome of this pathogen was sequenced and analyzed. Phylogenomic analyses confirmed that the pathogen present in nodular thelitis and tuberculoid scrotitis is a distinct species related to the leprosy bacilli and Mycobacterium haemophilum.
Ancient genomes reveal a high diversity of Mycobacterium leprae in medieval Europe
Studying ancient DNA allows us to retrace the evolutionary history of human pathogens, such as Mycobacterium leprae, the main causative agent of leprosy. Leprosy is one of the oldest recorded and most stigmatizing diseases in human history. The disease was prevalent in Europe until the 16 th century and is still endemic in many countries with over 200,000 new cases reported annually. Previous worldwide studies on modern and European medieval M.
Red squirrels in the British Isles are infected with leprosy bacilli
With the exception of armadillos in the Americas, leprosy infections are considered almost exclusively restricted to humans. Avanzi et al. examined warty growths on the faces and extremities of red squirrels in the British Isles and found that two species of leprosy-causing organisms were to blame (see the Perspective by Stinear and Brosch). Mycobacterium leprae in the southern population of Brownsea Island squirrels originated from a medieval human strain. M.
Show More
loading
Actions
Is this you?
As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.Get in touch with Charlotte
Contact Charlotte, search articles and posts on X, monitor coverage, and track replies from one place.
Learn more about Muck Rack