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charly acevedo on Muck Rack

charly acevedo

México
As seen in: BioRxiv, La Ranchera 1050
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Articles

Intestinal Epithelial PTPN2 Limits Pathobiont Colonization by Immune-Directed Antimicrobial Responses

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By Pritha Chatterjee, Marianne R. Spalinger, charly acevedo, Casey M. Gries
| BioRxiv
Abstract Background and Aims: Loss of activity of the inflammatory bowel disease (IBD) susceptibility gene, protein tyrosine phosphatase non-receptor type 2 (PTPN2), is associated with altered microbiome composition in both human subjects and mice. Further, expansion of the bacterial pathobiont, adherent-invasive E. coli (AIEC), is strongly linked to IBD pathogenesis.
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