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Cheng-Lin Yin

As seen in: ACS Publications
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Articles

One-Pot Three-Component Synthesis of Indolyl-4H-chromene-3-sulfonyl Fluoride: A Class of Important Pharmacophore

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By Richard Qin, Hua-Li Qin, Cheng-Lin Yin
| ACS Publications
A one-pot, sequential three-component reaction between salicylaldehyde, indole, and 2-bromoprop-2-ene-1-sulfonyl fluoride (BPESF) has been demonstrated for the synthesis of sulfonyl fluoride substituted 4H-chromene derivatives in moderate to excellent yields (45%–94%). This one-pot sequential method features easily available starting materials, wide substrate scope, mild conditions, and great efficiency.
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One-Pot Three-Component Synthesis of Indolyl-4H-chromene-3-sulfonyl Fluoride: A Class of Important Pharmacophore

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By Cheng-Lin Yin, Richard Qin, Hua-Li Qin
| dx.doi.org
A one-pot, sequential three-component reaction between salicylaldehyde, indole, and 2-bromoprop-2-ene-1-sulfonyl fluoride (BPESF) has been demonstrated for the synthesis of sulfonyl fluoride substituted 4H-chromene derivatives in moderate to excellent yields (45%–94%). This one-pot sequential method features easily available starting materials, wide substrate scope, mild conditions, and great efficiency.
Open in Who Shared Issue with article?
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