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Immunomodulatory responses and mitigation of Vibrio parahaemolyticus infection in white shrimp induced by heat-killed Vibrio parahaemolyticus
Abstract This study investigated the immunoprotective efficacy of heat-killed Vibrio parahaemolyticus (HVp) at two concentrations, 1 × 105 CFU/mL (HVp5) and 1 × 107 CFU/mL (HVp7), administered via intramuscular injection in Litopenaeus vannamei. Immune parameters, carbohydrate metabolism, bacterial clearance efficiency, histopathology, and survival following pathogen challenge were comprehensively evaluated.
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