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Chenwei Gu

As seen in: Wiley Online Library, PLOS, PLOS ONE, Frontiers, Frontiers in Immunology, MDPI, Dove Medical Press
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Articles by Chenwei Gu

TLN1 interacts with NGFR and suppresses the development of castration-resistant prostate cancer by upregulating NGFR

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By Sixin Li, Anjie Chen, Chen Guo, Chenwei Gu, Zhonghao Tang, Si Shen, Dongjie Yang, Yuanyuan Mi
| Frontiers in Immunology
Abstract Background: Prostate cancer (PCa) is a common malignant tumor in males, and castration-resistant prostate cancer (CRPC) represents an advanced stage with limited treatment options and poor prognosis. Talin-1 (TLN1) is a cytoskeletal protein implicated in tumor progression, but its specific role and mechanism in CRPC remain unclear. Methods: Mass spectrometry (MS) was used to analyze serum peptides from patients with hormone-sensitive prostate cancer (HSPC) and CRPC.
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Tropomyosin 3 Gene Fusions in Cancers: From Mechanisms to Treatments-A Comprehensive Review

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By Anjie Chen, Sixin Li, Chen Guo, Chenwei Gu
| Wiley Online Library Verified
1 Introduction Gene fusions constitute pivotal genomic alterations resulting from chromosomal rearrangements, which lead to the formation of hybrid genes [1]. These hybrid genes encode fusion proteins capable of disrupting normal cellular processes and contributing to oncogenesis. Of particular interest, tropomyosin 3 (TPM3) gene fusions have been identified as significant contributors to tumorigenesis.
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Novel Strategies for Precision Diagnosis and Treatment of Prostate Can

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By Si Shen, Chenwei Gu, Sixin Li, Zhonghao Tang
| Dove Medical Press
Back to Journals » International Journal of Nanomedicine » Volume 21 Authors Tang Z, Shen S, Gu C, Li S, Ni J, Yang D, Mi Y Received 5 November 2025 Accepted for publication 13 January 2026 Published 22 January 2026 Volume 2026:21 Pages 1—27 DOI https://doi.org/10.2147/IJN.S579436 Checked for plagiarism Yes Review by Single anonymous peer review Peer reviewer comments 2 Editor who approved publication: Professor Eng San Thian Zhonghao Tang,1,2,* Si Shen,1,2,* Chenwei Gu,1,2,*...
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Impact of calcined bauxite aggregates on the polishing resistance and skid resistance performance of SMA-7 asphalt mixtures

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By Pengfei Li, Nan Mao, Chenwei Gu, Lingkun Kong
| PLOS ONE
Loading metrics Open Access Peer-reviewed Research Article Citation: Li P, Kong L, Mao N, Gu C (2025) Impact of calcined bauxite aggregates on the polishing resistance and skid resistance performance of SMA-7 asphalt mixtures. PLoS One 20(8): e0329579. https://doi.org/10.1371/journal.pone.0329579 Editor: Jiaolong Ren, Shandong University of Technology, CHINA Received: May 13, 2025; Accepted: July 18, 2025; Published: August 5, 2025 Copyright: © 2025 Li et al.
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The association between CD40 gene polymorphisms and the risk of cancer based on a meta-analysis

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By Sixin Li, Xichen Feng, Anjie Chen, Jiandong Gui, Chenwei Gu, Chen Guo, Yujie Deng, Yuanyuan Mi
| Frontiers
Abstract Background: CD40, a constituent of the tumor necrosis factor (TNF) receptor superfamily, exhibits variable expression across different cancer types. It plays a role in mediating tumor cell proliferation, apoptosis, and survival, as well as antitumor immune responses and the tumor microenvironment. Although some studies have suggested a potential association between CD40 gene polymorphisms and cancer risk, definitive conclusions remain elusive.
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Driver Behavior Mechanisms and Conflict Risk Patterns in Tunnel-Interchange Connecting Sections: A Comprehensive Investigation Based on the Behavioral Adaptation Theory

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By Chenwei Gu, Xingliang Liu, Nan Mao
| MDPI
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
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Investigation of Car following and Lane Changing Behavior in Diverging Areas of Tunnel-Interchange Connecting Sections Based on Driving Simulation

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By Zhenhua Sun, Jinliang Xu, Chenwei Gu, Tian Tian Xin
| MDPI
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
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Investigation of Car Following and Lane Changing Behavior in Diverging Areas of Tunnel-Interchange Connecting Sections Based on Driving Simulation

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By Zhenhua Sun, Jinliang Xu, Chenwei Gu, Tian Tian Xin
| Preprints.org
Preprint Article Version 1 This version is not peer-reviewed Version 1 : Received: 18 April 2024 / Approved: 18 April 2024 / Online: 18 April 2024 (11:24:25 CEST) Sun, Z.; Xu, J.; Gu, C.; Xin, T.; Zhang, W. Investigation of Car Following and Lane Changing Behavior in Diverging Areas of Tunnel-Interchange Connecting Sections Based on Driving Simulation. Preprints 2024, 2024041230. https://doi.org/10.20944/preprints202404.1230.v1 Sun, Z.; Xu, J.; Gu, C.; Xin, T.; Zhang, W.
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Injury Risk Assessment and Interpretation for Roadway Crashes Based on Pre-Crash Indicators and Machine Learning Methods

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By Chenwei Gu, Jinliang Xu, Shuqi Li, Chao Gao
| MDPI
Author / Affiliation / Email Search Type Submit to this Journal Review for this Journal Edit a Special Issue Article Menu /ajax/scifeed/subscribe Altmetric share Share announcement Help format_quote Cite thumb_up ... Endorse textsms ... Comment Need Help? Support Find support for a specific problem in the support section of our website. Get Support Feedback Please let us know what you think of our products and services.
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Multivariate analysis of roadway multi-fatality crashes using association rules mining and rules graph structures: A case study in China

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By Chenwei Gu, Jinliang Xu, Chao Gao, Minghao Mu
| PLOS
5.1 Analysis of RGSs Based on the generated rule sets, the Gephi interactive network visualization platform is used to create four directed rule network structures according to different graph structure properties, as shown in Fig 2. Each graphic structure contains 1515 nodes and 5340 edges, of which 63 nodes represent crash factors occurring in the rules, with sizes proportional to the node properties. The remaining 1452 nodes represent independent rules connecting the LHS and RHS items.
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Modelling carbon emissions of diesel trucks on longitudinal slope sections in China

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By Yaping Dong, Jinliang Xu, Chenwei Gu
| PLOS
Loading metrics Open Access Peer-reviewed Research Article Yaping Dong, Jinliang Xu , Chenwei Gu Yaping Dong, Jinliang Xu, Chenwei Gu Published: June 16, 2020 https://doi.org/10.1371/journal.pone.0234789 Figures Abstract Carbon emissions are the primary reason that contributes to global warming. The gradient has a significant impact on the carbon dioxide (CO2) emissions produced by trucks.
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