Chenyin Zhang

Abstract Lipopolysaccharide (LPS), a potent immunogenic component of the outer membrane of Gram-negative bacteria, triggers severe inflammation and organ failure even at nanomolar concentrations. However, neutralizing LPS in vivo remains challenging due to the high abundance of other biomolecules in biological fluids, which interfere with LPS detoxification.

Corresponding Author Xiaoyuan Chen Departments of Diagnostic Radiology, Surgery, Chemical and Biomolecular Engineering, and Biomedical Engineering, Yong Loo Lin School of Medicine and Faculty of Engineering, National University of Singapore, Singapore, 119074 Singapore Nanomedicine Translational Research Program, NUS Center for Nanomedicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, 117597 Singapore Clinical Imaging Research Centre, Centre for Translational...

Graphical Abstract Antibacterial Strategies An innovative nanozyme-armed phage (phage@Pd) system is fabricated for combating bacterial infection, as reported by Zhengwei Mao and co-workers in article number 2301349. The phage@Pd preserves the function of phages to achieve precise recognition and adhesion to bacteria.