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Chenying Xu

As seen in: Nature, Taylor & Francis Online, Dove Medical Press
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Articles

CBX4 stabilizes NEUROD1 through SUMO-ubiquitin crosstalk to delay β-cell senescence

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By Yan Liu, Hongjin Chen, Yimeng Qin, Chenying Xu, Kun Gao, Yuncai Zhou, Yue Yang, Jianxing Liu, Yi Pan, Yanfeng Zhang, Xiaohang Zhou, Hailiang Liu, Liang Jin, Fangfang Zhang, Linming Su, Qianxing Hu, Fengjiao Huo
| Nature Verified
Abstract Aging-associated β-cell senescence is a key driver of type 2 diabetes mellitus (T2DM). However, its associated molecular mechanisms remain poorly explored. This study identifies Chromobox 4 (CBX4), a Polycomb group protein with SUMO E3 ligase activity, as an essential regulator of β-cell aging and function. The results show that CBX4 expression progressively downregulates in both aged and diabetic pancreatic islets.
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Full article: Construction of a Prediction Model for Sleep Quality in Embryo Repeated Implantation Failure Patients Undergoing Assisted Reproductive Technology Based on Machine Learning: A Single-Center Retrospective Study

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By Yanjun Zhao, Chenying Xu, Ningxin Qin, Lina Bai
| Taylor & Francis Online
Abstract Objective Constructing a predictive model for sleep quality in embryo Repeated Implantation Failure(RIF) patients using multiple machine learning algorithms, verifying its performance, and selecting the optimal model.
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Construction of a Prediction Model for Sleep Quality in Embryo Repeate

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By Yanjun Zhao, Chenying Xu, Ningxin Qin, Lina Bai
| Dove Medical Press
Yanjun Zhao,1,* Chenying Xu,1,* Ningxin Qin,2,* Lina Bai,1 Xuelu Wang,1 Ke Wang2 1Operating Room, Shanghai Key Laboratory of Maternal Fetal Medicine, Shanghai Institute of Maternal-Fetal Medicine and Gynecologic Oncology, Shanghai First Maternity and Infant Hospital, School of Medicine, Tongji University, Shanghai, 200092, People’s Republic of China; 2Reproductive Medicine Center, Shanghai Key Laboratory of Maternal Fetal Medicine, Shanghai Institute of Maternal-Fetal Medicine and...
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