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RUNX2 promotes osteoclast differentiation and bone resorption via the newly identified LncRNA-ROD : implications for alveolar remodeling
Abstract Delayed tooth eruption is a hallmark of cleidocranial dysplasia (CCD) caused by RUNX2 haploinsufficiency, yet the underlying molecular mechanism remains undefined. Here, we show that RUNX2 regulates osteoclast-mediated alveolar bone remodeling, a process closely associated with tooth eruption. Runx2+/− mice exhibit impaired osteoclast differentiation and reduced alveolar bone resorption, resulting in delayed mandibular molar eruption—a phenotype that recapitulates human CCD.
Optimizing Oxygen Redox Activity by Local Chemical Disorder toward Robust Co‐Free Li‐Rich Cathode with High Voltage Stability
Conflict of Interest The authors declare no conflict of interest. Supporting Information Filename Description adma202414443-sup-0001-SuppMat.docx16.7 MB Supporting Information References 1a) , , , , , , , , , , Nat. Mater. 2023, 22, 1370; b) , , , , , , , , , , , , , , , Nat. Commun. 2024, 15, 1288; c) , , Nat. Energy 2018, 3, 373; d) , , , , , , , , , , , Nat. Rev. Mater. 2022, 7, 522. 2, , , , , , Nat. Chem. 2016, 8, 692. 3a) , , , , , , , , , , , , Science 2015, 350, 1516; b) , , , , , , , , , , Adv.
Intrinsic Highly Conductive and Mechanically Robust Li‐Rich Cathode Materials Enabled by Microstructure Engineering for Enhanced Electrochemical Properties
Conflict of Interest The authors declare no conflict of interest. Supporting Information Filename Description adfm202308494-sup-0001-SuppMat.pdf3.8 MB Supporting Information adfm202308494-sup-0002-MovieS1.avi2.5 MB Supplemental Movie 1 References 1a) , , , , , , , , , , , , Adv. Mater. 2021, 33, 2005937; b) , , , , , Adv. Energy Mater. 2016, 6, 1501010; c) , , J. Electrochem. Soc. 2015, 162, A2490. 2a) , , , , , , Nat. Chem. 2016, 8, 692; b) , , , , , , , , , , , , , , Nat. Commun. 2018, 9, 947.
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