Chet Oon on Muck Rack

Chet Oon

As seen in: Cancer Discovery
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Articles

Stromal KITL/SCF promotes pancreas tissue homeostasis and restrains tumor progression

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By M. Kathrina Onate, Chet Oon, Sohinee Bhattacharyya, Vivien Low
| biorxiv.org
Abstract Components of normal tissue architecture serve as barriers to tumor progression. Inflammatory and wound-healing programs are requisite features of solid tumorigenesis, wherein alterations to immune and non-immune stromal elements enable loss of homeostasis during tumor evolution. The precise mechanisms by which normal stromal cell states limit tissue plasticity and tumorigenesis, and which are lost during tumor progression, remain largely unknown.
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A Stromal Lysolipid-Autotaxin Signaling Axis Promotes Pancreatic Tumor Progression

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By Vinay Bulusu, Francesca R. Auciello, Chet Oon, Jacqueline Tait-Mulder
| Cancer Discovery Verified
Research Briefs Francesca R. Auciello, Vinay Bulusu, Chet Oon, Jacqueline Tait-Mulder, Mark Berry, Sohinee Bhattacharyya, Sergey Tumanov, Brittany L. Allen-Petersen, Jason Link, Nicholas D. Kendsersky, Esmee Vringer, Michelle Schug, David Novo, Rosa F. Hwang, Ronald M. Evans, Colin Nixon, Craig Dorrell, Jennifer P. Morton, Jim C. Norman, Rosalie C. Sears, Jurre J. Kamphorst and Mara H.
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