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Chi Jung

As seen in: Frontiers
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Articles

Conditional Knockout of Bmal1 in Corticotropin-Releasing Factor Neurons Does Not Alter Sleep-Wake Rhythm in Mice

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By Christopher S. Colwell, Matt Carter, Michihiro Mieda, Chi Jung
| Frontiers
Introduction Physiology and behavior, such as sleep and wakefulness, exhibit daily variations that are controlled by the circadian clock. In mammals, almost all cells contain the circadian clock that is thought to generate approximately 24-h rhythms by the transcription–translation feedback loop of several clock genes such as Bmal1, Clock, Period, and Cryptochrome (Reppert and Weaver, 2002). The circadian clocks are present in a variety of tissues and cells.
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