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Chibbhi Bhaskar on Muck Rack

Chibbhi Bhaskar

As seen in: BioRxiv
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Articles

N-glycosylation Enables Smut Fungal Nge1 Orthologs to Prevent the Escape of Maize Evolved-PMEIs

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By Wei-Lun Tsai, Chibbhi Bhaskar, Minh-Quang Chau, Ooi-Kock Teh
| BioRxiv
Abstract Cell wall integrity (CWI) is regulated by the coordinated activity of CW-modifying enzymes, including pectin methylesterases (PMEs) and their inhibitors (PMEIs). PMEs de-methylesterify pectins, making them more susceptible to degradation and loosening the CW, facilitating pathogen invasion. Conversely, PMEIs inhibit PMEs, reinforcing the CWI and enhancing plant defense. However, how biotrophic pathogens overcome PMEI-mediated defense remains unclear.
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