Chih-Ying Chen

1 Introduction Traumatic brain injury (TBI) is a leading cause of death and long-term disability in industrialized countries.[1] The global cost of TBI is estimated to be as high as $400 billion due to its lasting effects on mortality, cognitive performance, and morbidity.[2] There are currently no effective strategies to promote nerve regeneration or functional recovery in TBI.[3] After injury, activated stellate cells and infiltrating microglia exacerbate inflammation, leading to glial...

1 Introduction X-linked retinoschisis (X-linked juvenile retinoschisis; XLRS) is an early-onset X-linked inherited retinal disorder that leads to structural splitting of the neurosensory retina and severe visual impairment.[1] Retinoschisin-1 (RS1) is a 224-amino acid protein consisting of two conserved regions: an N-terminal signal sequence (aa 1–23) and a discoidin domain (aa 64–219).

All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.